Project Description: The WHO 2013 “Guidance Notes for Estimating the Longevity of Long-Lasting Insecticidal Nets in Malaria Control” set several priorities for operational research. In response to this guidance we are carrying out a controlled study in the semi-field to understand the determinants of net entry for partially resistant and highly resistant (30% an 70% survival to exposure with discriminating dose of deltamethrin) Anopheles arabiensis. The following outcome variables are measured with nets with different holes and... The WHO 2013 “Guidance Notes for Estimating the Longevity of Long-Lasting Insecticidal Nets in Malaria Control” set several priorities for operational research. In response to this guidance we are carrying out a controlled study in the semi-field to understand the determinants of net entry for partially resistant and highly resistant (30% an 70% survival to exposure with discriminating dose of deltamethrin) Anopheles arabiensis. The following outcome variables are measured with nets with different holes and insecticidal concentrations: 1) Personal protection to the user, 2) Overall insecticidal effect that will protect all members of the community, and 3) Predicted proportion reduction in entomological inoculation rate (EIR).
Principal Investigator : Sarah Moore
Department Name : EHES
Time frame: (2014-02-01) - (2019-01-31)